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The genetics of epilepsy in the British Alsatian
Author(s) -
Falco Marsha J.,
Barker John,
Wallace Margaret E.
Publication year - 1974
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1974.tb05651.x
Subject(s) - pedigree chart , medicine , breed , inheritance (genetic algorithm) , epilepsy , population , genetics , gene , psychiatry , biology , environmental health
Study of the pedigrees of a population of normal and epileptic Alsatians has revealed that there is a genetic basis for the condition in this breed, and that this basis is more complex than has hitherto been suggested. A preponderance of males is affected and there is strong evidence for additive factors determining the age at which animals first show clinical signs, and for the effect of one or more major genes. Only an objective test‐mating programme is likely to delineate the true mode of inheritance.