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Evaluation of the antimicrobial activities of chlorhexidine gluconate, sodium hypochlorite and octenidine hydrochloride in vitro
Author(s) -
Tirali Resmiye E.,
Bodur Haluk,
Sipahi Bilge,
Sungurtekin Elif
Publication year - 2013
Publication title -
australian endodontic journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.703
H-Index - 34
eISSN - 1747-4477
pISSN - 1329-1947
DOI - 10.1111/j.1747-4477.2010.00266.x
Subject(s) - enterococcus faecalis , antimicrobial , sodium hypochlorite , candida albicans , chlorhexidine , chemistry , agar , microbiology and biotechnology , agar diffusion test , chlorhexidine gluconate , agar plate , medicine , dentistry , biology , bacteria , escherichia coli , biochemistry , organic chemistry , genetics , gene
The objective of this study was to compare the antimicrobial activity of sodium hypochlorite (NaOCl), chlorhexidine gluconate (CHX) and octenidine hydrochloride (OCT) in different concentrations against endodontic pathogens in vitro . Agar diffusion procedure was used to determine the antimicrobial activity of the tested materials. Enterococcus faecalis , Candida albicans and the mixture of these were used for this study. In the agar diffusion test, 5.25% NaOCl exhibited better antimicrobial effect than the other concentrations of NaOCl for all strains. All concentrations of OCT were effective against C. albicans and E. faecalis . Some 0.2% CHX was ineffective on all microorganisms. Antibacterial effectiveness of all experimental solutions decreased on the mixture of all strains. Decreasing concentrations of NaOCl resulted in significantly reduced antimicrobial effect.