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An agar diffusion study comparing the antimicrobial activity of Nanoseal with some other endodontic sealers
Author(s) -
AalSaraj Ali Burak,
Ariffin Zaihan,
Masudi Sam'an Malik
Publication year - 2012
Publication title -
australian endodontic journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.703
H-Index - 34
eISSN - 1747-4477
pISSN - 1329-1947
DOI - 10.1111/j.1747-4477.2010.00241.x
Subject(s) - streptococcus sobrinus , enterococcus faecalis , agar , agar diffusion test , antimicrobial , microbiology and biotechnology , chemistry , pseudomonas aeruginosa , agar plate , significant difference , streptococcus mutans , escherichia coli , biology , bacteria , medicine , biochemistry , genetics , gene
The aim of this study was to evaluate the antimicrobial activity of a new experimental nano‐hydroxyapatite epoxy resin‐based sealer (Nanoseal) with several other commercially available sealers; AH26, Tubliseal, Sealapex and Roekoseal against Enterococcus faecalis, Pseudomonas aeruginosa, Streptococcus mutans, Streptococcus sobrinus and Escherichia coli for up to 7 days. Agar diffusion was used in this study. Fifty Muller‐Hinton agar plates were prepared and divided into five experimental groups ( n = 10), for each micro‐organism. Another 10 agar plates were used as positive and negative controls. Endodontic sealers were tested against each micro‐organism. Inhibition zones produced were recorded. The results of this study showed that all test materials exhibited inhibition zones towards the tested micro‐organisms for 7 days except for Roekoseal, which showed no inhibition zones. Nanoseal and AH26 exhibited similar zones of inhibition. Significant difference was found between Nanoseal and the other tested sealers ( P < 0.001).