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Determination of the minimum inhibitory concentration of four medicaments used as intracanal medication
Author(s) -
Pallotta Raul C.,
Ribeiro Mariangela S.,
De Lima Machado Manoel E.
Publication year - 2007
Publication title -
australian endodontic journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.703
H-Index - 34
eISSN - 1747-4477
pISSN - 1329-1947
DOI - 10.1111/j.1747-4477.2007.00095.x
Subject(s) - calcium hydroxide , enterococcus faecalis , ciprofloxacin , minimum inhibitory concentration , bacteroides fragilis , iodoform , pseudomonas aeruginosa , chemistry , microbiology and biotechnology , iodine , metronidazole , nuclear chemistry , bacteria , antibiotics , biology , biochemistry , escherichia coli , organic chemistry , genetics , gene
The aim of this study was to determine the minimum inhibitory concentration (MIC) of iodoform, calcium hydroxide, IKI (iodine potassium iodine) and CFC (ciprofloxacin, Flagyl (metronidazole) and calcium hydroxide) required to kill S. aureus, Pseudomonas aeruginosa, Enterococcus faecalis and B. fragilis . In the experiment, medicaments were added to bacterial species into test tubes, in 10 different concentrations. The MIC was the lowest concentration of the drug at which bacterial growth could not be observed. In this investigation, CFC was the most effective medicament against all bacteria. All drugs were able to eliminate E. faecalis and B. fragilis , while IKI was not effective against S. aureus . IKI and calcium hydroxide were not able to eliminate P. aeruginosa as well.