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Effectiveness of a 2% chlorhexidine solution mixed with calcium hydroxide against Candida albicans
Author(s) -
AlNazhan Saad,
AlObaida Mohammed
Publication year - 2008
Publication title -
australian endodontic journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.703
H-Index - 34
eISSN - 1747-4477
pISSN - 1329-1947
DOI - 10.1111/j.1747-4477.2007.00091.x
Subject(s) - chlorhexidine , calcium hydroxide , candida albicans , chemistry , calcium , nuclear chemistry , microbiology and biotechnology , dentistry , medicine , biology , organic chemistry
The purpose of this investigation was to examine the in vitro susceptibility of Candida albicans to a mixture of chlorhexidine and calcium hydroxide using a tube dilution test. A suspension containing C. albicans was exposed to 2% chlorhexidine solution, calcium hydroxide paste and 2% chlorhexidine mixed with calcium hydroxide in plastic tissue culture wells. The tested agents were incubated with C. albicans for 1, 24, or 72 h. All agents were effective anti‐fungals at all experimental time periods tested, with the exception of exposure to calcium hydroxide for 1 h. A mixture of 2% chlorhexidine and calcium hydroxide therefore is a very effective anti‐fungal agent against C. albicans.