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Synthesis and Antifungal Activities of New Pyrazole Derivatives via 1,3‐dipolar Cycloaddition Reaction
Author(s) -
Zhang ChuanYu,
Liu XingHai,
Wang BaoLei,
Wang SuHua,
Li ZhengMing
Publication year - 2010
Publication title -
chemical biology and drug design
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 77
eISSN - 1747-0285
pISSN - 1747-0277
DOI - 10.1111/j.1747-0285.2010.00948.x
Subject(s) - cycloaddition , corynespora cassiicola , chemistry , maleimide , pyrazole , fungicide , 1,3 dipolar cycloaddition , antifungal , elemental analysis , organic chemistry , medicinal chemistry , combinatorial chemistry , biology , botany , microbiology and biotechnology , catalysis , leaf spot
A series of cycloadducts‐‐pyrazoles via 1,3‐dipolar cycloaddition reactions of generated nitrilimines with N‐(4‐chloro‐2‐fluorophenyl)maleimide were described. The novel compounds synthesized were characterized by 1 H NMR, MS, and elemental analysis. The fungicidal tests showed that most of the title compounds exhibit significant fungicidal activities against Corynespora cassiicola .