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Microwave‐Assisted Solid‐Phase Peptide Synthesis Utilizing N ‐Fmoc‐Protected ( α ‐aminoacyl)benzotriazoles
Author(s) -
Katritzky Alan R.,
Khashab Niveen M.,
Yoshioka Megumi,
Haase Danniebelle N.,
Wilson Krista R.,
Johnson Jodie V.,
Chung Alfred,
HaskellLuevano Carrie
Publication year - 2007
Publication title -
chemical biology and drug design
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 77
eISSN - 1747-0285
pISSN - 1747-0277
DOI - 10.1111/j.1747-0285.2007.00584.x
Subject(s) - solid phase synthesis , peptide synthesis , combinatorial chemistry , peptide , chemistry , phase (matter) , organic chemistry , biochemistry
A novel microwave‐assisted solid‐phase peptide synthesis utilizing N ‐Fmoc‐protected( α‐ aminoacyl)benzotriazoles was applied in the preparation of tri‐, tetra‐, penta‐, hexa‐, and heptapeptides in 71% average crude yield.