Premium
SAFETY EXAMINATION OF SOME EDIBLE OR MEDICINAL PLANTS AND PLANT CONSTITUENTS, PART 3
Author(s) -
HIRONO IWAO,
UCHIDA SHIGETOSHI HOSAKA EIJI,
TAKANASHI HITOSHI,
HAGA MASANOBU,
SAKATA MASAKATSU,
MORI HIDEKI,
TANAKA TAKUJI,
HIKINO HIROSHI
Publication year - 1980
Publication title -
journal of food safety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 43
eISSN - 1745-4565
pISSN - 0149-6085
DOI - 10.1111/j.1745-4565.1980.tb00397.x
Subject(s) - caffeic acid , edible plants , lathyrus , horticulture , food science , botany , basal (medicine) , biology , carcinogen , traditional medicine , chemistry , microbiology and biotechnology , medicine , biochemistry , insulin , antioxidant
The carcinogenicity of vicia, galanga, lathyrus and lycium, which are plants used as human food or in folk medicine, and of caffeic acid and prunasin, which are plant constituents, was examined in an inbred strain of ACI rats. Fresh plant materials were dried, milled and mixed with the rat basal diet in the ratio of 16% and 33% of the total. The plant constituents, caffeic acid and prunasin, were mixed with the basal diet in the ratio of 0.5% and 0.03%, respectively. These diets were administered to rats for periods ranging upward from 180 days. Carcinogenic activity was not observed with any of the plants or plant constituents.