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URINARY EXCRETION OF ANTIOXIDANTS IN HEALTHY HUMANS FOLLOWING QUEEN GARNET PLUM JUICE INGESTION: A NEW PLUM VARIETY RICH IN ANTIOXIDANT COMPOUNDS
Author(s) -
NETZEL MICHAEL,
FANNING KENT,
NETZEL GABRIELE,
ZABARAS DIMITRIOS,
KARAGIANIS GLORIA,
TRELOAR TONY,
RUSSELL DOUGAL,
STANLEY ROGER
Publication year - 2012
Publication title -
journal of food biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 47
eISSN - 1745-4514
pISSN - 0145-8884
DOI - 10.1111/j.1745-4514.2010.00522.x
Subject(s) - polyphenol , antioxidant , anthocyanin , food science , chemistry , prunus salicina , excretion , ingestion , grape seed extract , cyanidin , malondialdehyde , biochemistry , pharmacology , biology , prunus , botany , medicine , alternative medicine , pathology
In recent years, there has been intense interest in the potential health benefits of dietary derived plant polyphenols and antioxidants. A new variety of Prunus salicina , Queen Garnet plum (QGP), was developed as a high anthocyanin, high antioxidant plum, in a Queensland Government breeding program. Following consumption of 400 mL QGP juice (QGPJ; 1,117 mg anthocyanins) by two healthy male subjects, QGP anthocyanins (cyanidin‐3‐glucoside and cyanidin‐3‐rutinoside) were excreted mainly as methylated and glucuronidated metabolites in urine (0.5% of the ingested dose within 24 h). Furthermore, QGPJ intake resulted in a threefold increase in hippuric acid excretion (potential biomarker for total polyphenols intake and metabolite), an increased urinary antioxidant capacity and a decreased malondialdehyde excretion (biomarker for oxidative stress) within 24 h as compared with the polyphenol‐/antioxidant‐free control. Results from this pilot study suggest that metabolites, and not the native QGP anthocyanins/polyphenols, are most likely the bioactive compounds in vivo . PRACTICAL APPLICATIONS In recent years, there has been increasing consumer interest in antioxidant‐rich foods, which have guided breeders of different crops to consider antioxidant compounds, such as anthocyanins and other polyphenols, as interesting targets in breeding programs. In this manuscript, we are presenting for the first time (1) data about the outstanding antioxidant and anthocyanin content of Queen Garnet plum (QGP), a new variety of Prunus salicina , which was developed in a Queensland Government breeding program, and (2) data about the absorption and metabolism of QGP anthocyanins/antioxidants in healthy humans as assessed by their urinary excretion. The results of this initial work indicate that QGP and/or derived products could represent a new and promising source of anthocyanins as natural ingredients and colorants for the food and nutraceutical industries.