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ANTIOXIDANT ACTIVITY OF TRIPHALA A COMBINATION OF TERMINALIA CHEBULA, TERMINALIA BELLERICA AND EMBLICA OFFICINALIS
Author(s) -
SINGH RAJBIR,
SINGH BIKRAM,
KUMARB NEERAK,
ARORA SAROJ
Publication year - 2010
Publication title -
journal of food biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 47
eISSN - 1745-4514
pISSN - 0145-8884
DOI - 10.1111/j.1745-4514.2009.00326.x
Subject(s) - chemistry , terminalia chebula , antioxidant , traditional medicine , polyphenol , chloroform , acetone , lipid peroxidation , deoxyribose , biochemistry , chromatography , medicine , dna
The antioxidant, deoxyribose (site specific and nonsite specific) degradation, reducing power, chelating power and lipid peroxidation activities of Triphala powder extracted sequentially with methanol, acetone and chloroform were studied. The methanol and acetone extracts exhibited good antioxidant potential than the chloroform extract. The inhibitory potential was correlated with the total phenolic content in the respective extracts. It was observed that fractions were rich in polyphenolic content, thereby showed comparatively more effect than crude extract having less phenolic content.PRACTICAL APPLICATIONS As most of the cancer causing agents generates free radicals and cause DNA damage, the antioxidant and anti free radical scavenging activities of Triphala will help in its use as anticancer agent. Moreover, this study will have a great practical application in view of scientific validations of the use of Triphala as a protective agent for cancer.