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Effect of Various Anticoagulant Agents on Large‐Volume Leukocytapheresis Using New Cellsorba CS‐180S Filter
Author(s) -
Hohtatsu Katsura,
Yamaji Ken,
Yamada Risa,
Oda Keisuke,
Kageyama Michiaki,
Kusaoi Makio,
Onuma Shin,
Kawamoto Toshio,
Sugimoto Kaoru,
Sekiya Fumio,
Kon Takayuki,
Ogasawara Michihiro,
Kempe Kazuo,
Tsuda Hiroshi,
Takasaki Yoshinari
Publication year - 2011
Publication title -
therapeutic apheresis and dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 53
eISSN - 1744-9987
pISSN - 1744-9979
DOI - 10.1111/j.1744-9987.2011.00962.x
Subject(s) - medicine , anticoagulant , rheumatoid arthritis , low molecular weight heparin , enoxaparin sodium , sodium , volume (thermodynamics) , heparin , sodium carbonate , sodium citrate , pharmacology , chemistry , physics , organic chemistry , pathology , quantum mechanics
We conducted a study to evaluate the effect of various anticoagulant agents on large‐volume leukocytapheresis using the new Cellsorba CS‐180S Filter filled with a changed solution of sodium pyrosulfite and sodium carbonate. We conducted the study on a total of 12 cases of rheumatoid arthritis. As the anticoagulant agents we used sodium citrate, nafamostat mesilate and low molecular weight heparin. The new Cellsorba CS‐180S was safely used with the various blood anticoagulant agents. Also, through adjustment of the sodium citrate percentage to the blood flow volume, it is hypothesized that it is possible to increase the neutrophil removal rate.