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Efficacy of Separated System Continuous Venovenous Hemofiltration in Critical Acute Kidney Injury
Author(s) -
Susantitaphong Paweena,
Tiranathanagul Khajohn,
Srisawat Nattachai,
Katavetin Pisut,
Praditpornsilpa Kearkiat,
EiamOng Somchai
Publication year - 2011
Publication title -
therapeutic apheresis and dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 53
eISSN - 1744-9987
pISSN - 1744-9979
DOI - 10.1111/j.1744-9987.2010.00880.x
Subject(s) - medicine , acute kidney injury , renal replacement therapy , hemofiltration , critically ill , critical illness , intensive care medicine , observational study , surgery , hemodialysis
Integrated system continuous venovenous hemofiltration (CVVH), the most popularly utilized mode for continuous renal replacement therapy (CRRT), needs a sophisticated and expensive machine that is available only in limited critical care units. Separated system CVVH, which can be simply set up, might be an effectively alternative to CRRT. A one‐year prospective observational study regarding the efficacy of separated system CVVH was conducted with 192 critically ill patients with acute kidney injury. All patients underwent separated system CVVH with the pre‐dilution mode and a mean CVVH dose of 34.9 ± 2.7 mL/kg/h. The APACHE II score was 23.2 ± 8.4 and the Sequential Organ Failure Assessment score was 12.0 ± 4.3. No complications, including air‐embolism or circuit clotting, were observed and the survival rate was 32.3%. Separated system CVVH is simple, safe, and efficient and could provide cheaper treatments than the integrated system. It could thus be an effective, alternative treatment for critical acute kidney injury patients when the integrated mode is unavailable.