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A Case Report of Successful Long‐term Relapse Control by Protein‐A Immunoadsorption in an Immunosuppressive‐treated Patient With End‐stage Renal Disease Due to Wegener's Granulomatosis
Author(s) -
Koch Michael,
Kohnle Matthias,
Trapp Rudolf
Publication year - 2009
Publication title -
therapeutic apheresis and dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 53
eISSN - 1744-9987
pISSN - 1744-9979
DOI - 10.1111/j.1744-9987.2009.00670.x
Subject(s) - medicine , azathioprine , prednisone , cyclophosphamide , immunoadsorption , mycophenolate , end stage renal disease , hemodialysis , surgery , stage (stratigraphy) , disease , gastroenterology , immunology , transplantation , chemotherapy , antibody , paleontology , biology
A long‐term female hemodialysis patient with end‐stage renal disease due to Wegener's granulomatosis (WG) experienced a severe relapse when immunosuppressive therapy was switched from prednisone and cyclophosphamide to azathioprine maintenance therapy. Ten courses of protein A immunoadsorption therapy and switching immunosuppressive therapy to mycophenolate mofetil have proved to be very successful and free of side effects. The patient has fully recovered from all clinical WG symptoms and is still in remission ten months after the treatment.