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Advances in the Plant Isoprenoid Biosynthesis Pathway and Its Metabolic Engineering
Author(s) -
LIU Yan,
WANG Hong,
YE HeChun,
LI GuoFeng
Publication year - 2005
Publication title -
journal of integrative plant biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.734
H-Index - 83
eISSN - 1744-7909
pISSN - 1672-9072
DOI - 10.1111/j.1744-7909.2005.00111.x
Subject(s) - biosynthesis , terpenoid , metabolic engineering , metabolic pathway , cytosol , biochemistry , enzyme , gene , biology , chemistry , computational biology
Although the cytosolic isoprenoid biosynthetic pathway, mavolonate pathway, in plants has been known for many years, a new plastidial 1–deoxyxylulose‐5‐phosphate (DXP) pathway was identified in the past few years and its related intermediates, enzymes, and genes have been characterized quite recently. With a deep insight into the biosynthetic pathway of isoprenoids, investigations into the metabolic engineering of isoprenoid biosynthesis have started to prosper. In the present article, recent advances in the discoveries and regulatory roles of new genes and enzymes in the plastidial isoprenoid biosynthesis pathway are reviewed and examples of the metabolic engineering of cytosolic and plastidial isoprenoids biosynthesis are discussed. (Managing editor: Wei WANG)