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Surface Mineralization of Hydrogels Through Octacalcium Phosphate
Author(s) -
Guha Avijit,
Sinha Arvind
Publication year - 2010
Publication title -
international journal of applied ceramic technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 57
eISSN - 1744-7402
pISSN - 1546-542X
DOI - 10.1111/j.1744-7402.2010.02543.x
Subject(s) - self healing hydrogels , octacalcium phosphate , mineralization (soil science) , materials science , scaffold , tissue engineering , chemical engineering , simulated body fluid , biomineralization , phosphate , biomedical engineering , chemistry , composite material , polymer chemistry , calcium , organic chemistry , medicine , scanning electron microscope , nitrogen , metallurgy , engineering
Simulated body fluid‐induced nucleation and growth of octacalcium phosphate (OCP) on polyvinyl alcohol–hydroxyapatite (HA) hydrogels has been described and discussed in the present manuscript. Bulk mineralization of hydrogels is well reported in the literature for structural tissue engineering applications. However, a good interfacing between hydrogel scaffolds and biological organ, such as bone, could only be achieved through a suitable surface chemistry modification of the scaffold. OCP, a precursor to biological HA, may be an appropriate component of the hydrogel's surface likely to be used as a scaffold for bone tissue engineering.