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Cell Proliferation of Human Fibroblasts on Alumina and Hydroxyapatite‐Based Ceramics with Different Surface Treatments †
Author(s) -
Marchi Juliana,
Delfino Carina S.,
Bressiani José C.,
Bressiani Ana H. A.,
Marques Márcia M.
Publication year - 2010
Publication title -
international journal of applied ceramic technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 57
eISSN - 1744-7402
pISSN - 1546-542X
DOI - 10.1111/j.1744-7402.2009.02388.x
Subject(s) - biocompatibility , materials science , scanning electron microscope , ceramic , biocompatible material , alumina ceramic , substrate (aquarium) , biomedical engineering , chemical engineering , nuclear chemistry , metallurgy , composite material , chemistry , medicine , oceanography , engineering , geology
Biocompatibility is an important characteristic of dental implant material, and in vitro tests are required to elucidate the interaction between these materials and human tissues. Cell proliferation assays were done with fibroblasts plated on the surface of alumina and hydroxyapatite sintered samples, each with a different surface treatment (sintered, rectified, or polished). After 1, 2, and three days, the samples were prepared for scanning electron microscopy observations. The data were compared by analysis of variance followed by Tukey's test. It was concluded that neither the hydroxyapatite or alumina substrate is cytotoxic, and hydroxyapatite is more biocompatible than alumina.