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4‐Alkoxy‐2‐methylthiopyrrolo‐[2,3‐d]‐pyrimidines. A new series of anti‐cytokinins
Author(s) -
WILCOX E. J.,
WAIN R. L.
Publication year - 1982
Publication title -
annals of applied biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 80
eISSN - 1744-7348
pISSN - 0003-4746
DOI - 10.1111/j.1744-7348.1982.tb01954.x
Subject(s) - alkoxy group , cytokinin , steric effects , biology , pyrimidine , biological activity , stereochemistry , biochemistry , chemistry , in vitro , organic chemistry , auxin , alkyl , gene
SUMMARY A series of 4‐alkoxy‐2‐methylthiopyrrolo[2,3‐d] pyrimidines having alkoxy groups from methoxy to hexyloxy along with the parent 4‐hydroxy compound have been tested for cytokinin and anticytokinin activity using tobacco tissue culture. None of the compounds showed any cytokinin activity but several of the compounds were strongly active as anticytokinins, the most active was 4‐pentyloxy‐2‐methyl‐thiopyrrolo[2,3‐d] pyrimidine. Increasing or decreasing the chain length resulted in a lowering of activity; the hydroxy and methoxy compounds were totally inactive over the concentration range tested. The results are discussed in relation to steric and other considerations.