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The cytokinin activities of 6‐α‐alkylbenzyloxypurines
Author(s) -
WILCOX E. J.,
SELBY C.,
WAIN R. L.
Publication year - 1981
Publication title -
annals of applied biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 80
eISSN - 1744-7348
pISSN - 0003-4746
DOI - 10.1111/j.1744-7348.1981.tb03015.x
Subject(s) - cytokinin , biology , steric effects , alkyl , methylene , homologous series , stereochemistry , medicinal chemistry , biochemistry , auxin , organic chemistry , chemistry , gene
SUMMARY The homologous series of 6‐α‐ n ‐alkylbenzyloxypurines with alkyl groups (—(CH 2 ) n CH 3 ) from n = 0 to n = 11 have been prepared and examined in three tests for cytokinin activity. The parent benzyloxypurine was also included in the tests. Substituting methyl (n = 0) into the methylene group of 6‐benzyloxypurine removed activity almost completely; thereafter, increasing the size of the alkyl group (n = 1–5) gave compounds which were active in all tests, the butyl (n = 3) and pentyl (n = 4) derivatives being more active than 6‐benzyloxypurine itself. Activity then fell as the series was ascended; the higher homologues (n = 8–11) being completely inactive. The results are discussed in relation to steric and other considerations.