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Investigations on fungicides: X. The antifungal activity of 2‐deoxy‐D‐glucose
Author(s) -
ATKIN R. K.,
SPENCER D. M.,
WAIN R. L.
Publication year - 1964
Publication title -
annals of applied biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 80
eISSN - 1744-7348
pISSN - 0003-4746
DOI - 10.1111/j.1744-7348.1964.tb07257.x
Subject(s) - biology , glomerella cingulata , aspergillus niger , botrytis cinerea , fungicide , mycelium , cladosporium , spore germination , fungi imperfecti , sclerotinia , verticillium , botany , alternaria , botrytis , spore , aspergillus , horticulture , food science , colletotrichum gloeosporioides
SUMMARY The fungitoxicity of 2‐deoxy‐D‐glucose was examined in spore germination tests using Botrytis cinerea, B. fabae, Alternaria brassicicola, Aspergillus niger, Cladosporium cucumerinum, C. fulvum, Sclerotinia fructigena, Verticillium albo‐atrum and Glomerella cingulata. It proved to be toxic, at concentrations below 10 μg./ml., to all of these fungi except G. cingulata which was resistant to concentrations up to 2000 μg./ml. The effect of a‐deoxy‐D‐glucose on the mycelial growth of these fungi was assessed and again G. cingulata proved to be resistant to high concentrations of the compound, as also did A. niger. The results are discussed in relation to the known inhibitory nature of 2‐deoxy‐D‐glucose in other systems.