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Statistical Aspects of the Independent Joint Action of Poisons, Particularly Insecticides
Author(s) -
Plackett R. L.,
Hewlett P. S.
Publication year - 1948
Publication title -
annals of applied biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 80
eISSN - 1744-7348
pISSN - 0003-4746
DOI - 10.1111/j.1744-7348.1948.tb07379.x
Subject(s) - biology , bivariate analysis , toxicology , statistics , correlation , measure (data warehouse) , correlation coefficient , joint (building) , action (physics) , bliss , mathematics , econometrics , computer science , physics , architectural engineering , geometry , quantum mechanics , engineering , programming language , database
Bliss's (1939) statistical treatment of the hypothesis of the independent joint action of poisons is extended and revised. The possibility of negative correlation in resistance is considered, and the bivariate normal correlation coefficient is used to measure correlation in resistance. There are interesting characteristics of the dosage‐mortality curve for a mixture of poisons the resistances to which are log‐normally distributed: these are described. The question of whether a mixture of poisons is more toxic if they act similarly or independently is discussed.