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Physical Factors Affecting the Toxicity of Sprays to Stored Product Insects
Author(s) -
Hewlett P. S.
Publication year - 1948
Publication title -
annals of applied biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 80
eISSN - 1744-7348
pISSN - 0003-4746
DOI - 10.1111/j.1744-7348.1948.tb07352.x
Subject(s) - active ingredient , ingredient , toxicology , biology , statistics , mathematics , food science , bioinformatics
The problem of whether a given amount of active ingredient is more effectively applied in concentrated or dilute form is discussed. If y is percentage mortality and x 1 and x 2 are respectively log‐concentration of active ingredient and log‐volume (or deposit) of insecticide applied, y may be regarded as a uniform, continuous function of x 1 and x 2 . The amount of active ingredient is constant, i.e. x 1 + x 2 = k , so that dx/dx 1 =−dy/dx 2 =δy/δx 1 −δy/δx 2 Probit mortality, Y , can be substituted for y in (4). Thus, whether an active ingredient is better applied in concentrated or dilute form depends on the relative magnitudes of ∂ y /∂ x 1 and ∂ y /∂ x 2 , or of ∂ Y /∂ x 1 and ∂ Y /∂ x 2 . Equation (4) is true whenever an insecticide consists of an active ingredient in a diluent, whatever the dosage‐mortality relationship. Previous work is discussed in the light of (4) and its probit form, and it appears that the concentration at which an active ingredient is best applied can depend upon the nature and quantity of the active ingredient, and the method of application of the spray. There may be other facto*** The probit form of (4) is applied to the probit plane and confirmed experimentally. Flour beetles, Tribolium castaneum Herbst were sprayed with pyrethrins in Shell oil P 31, and it was found that ∂ Y /∂ x 1 > ∂ Y /∂ x 2 , so that a given quantity of pyrethrins was more toxic in concentrated solution than in dilute.

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