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No association between transmembrane protein‐tyrosine phosphatase receptor type C (PTPRC) exon A 77C>G transversion and liver transplant rejection
Author(s) -
Thude H.,
Schipler A. D.,
Treszl A.,
Sterneck M.,
Nashan B.
Publication year - 2012
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.2012.01119.x
Subject(s) - transversion , exon , biology , genotype , population , medicine , endocrinology , genetics , gene , environmental health
Summary This study was carried out to evaluate the association between 77C>G transversion (rs17612648) in exon A of the PTPRC gene and liver transplant rejection. No significant differences in genotype and allele frequencies of the 77C>G transversion were detected between recipients without rejection ( n = 106) and recipients with rejection ( n = 104). In conclusion, there was no evidence for the contribution of the 77C>G transversion in susceptibility to liver transplant rejection in a Caucasian population.