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Mannose‐binding lectin (MBL2) polymorphisms and inflammation in hypertensive patients
Author(s) -
Schreiber R.,
CamposCoelho A. V.,
Brandão L.,
Guimarães R. L.,
Kamada A. J.,
FerreiraSae M. C.,
MatosSouza J. R.,
Cipolli J. A.,
de LimaFilho J. L.,
Crovella S.,
Nadruz W.
Publication year - 2011
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.2011.01036.x
Subject(s) - mannan binding lectin , lectin , inflammation , genotype , medicine , mannose , immunology , biology , biochemistry , gene
Summary We investigated the possible role of Mannose binding lectin 2 ( MBL2 ) functional polymorphisms in the prevalence of hypertension and hypertensive end‐organ damage in 300 hypertensive patients and 313 normotensive individuals from Southern Brazil. Hypertensive subjects with MBL2 AO/OO genotypes presented lower C‐reactive protein levels than AA individuals and consequently lower inflammatory status.