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Association between interleukin‐4 gene polymorphisms and intracerebral haemorrhage in Korean population
Author(s) -
Park H. J.,
Kim M. J.,
Kang S. W.,
Kim S. K.,
Lee J. S.,
Park H. K.,
Yoo S. D.,
Kim D. H.,
Yun D. H.,
Kim H. S.,
Kim J. W.,
Chung J. H.,
Jeong Y. S.
Publication year - 2011
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.2011.01010.x
Subject(s) - haplotype , single nucleotide polymorphism , gene , medicine , polymorphism (computer science) , genetics , intracerebral hemorrhage , stroke (engine) , korean population , ischemic stroke , biology , gastroenterology , allele , genotype , ischemia , mechanical engineering , subarachnoid hemorrhage , engineering
Summary Interleukin‐4 ( IL4 ) polymorphisms (rs2243250, rs2070874) were analysed in Korean patients with ischaemic stroke (IS) ( n = 119) and intracerebral haemorrhage (ICH) ( n = 79), and age‐matched controls ( n =267, IS; n = 401, ICH) using direct sequencing. Both single nucleotide polymorphisms and their haplotypes were associated with ICH, but not IS.