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The HLA‐B*83:01 allele is generated by a gene conversion event including whole of exon 2 and partial introns 1 and 2 between B*44 and B*56 alleles
Author(s) -
Cervera I.,
Herraiz M. A.,
Vidart J. A.,
Peñaloza J.,
MartinezLaso J.
Publication year - 2011
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.2010.00971.x
Subject(s) - allele , intron , exon , genetics , gene conversion , biology , gene , human leukocyte antigen , hla b , hla b antigens , antigen
Summary Several studies have indicated the gene conversion as the most important mechanism about the MHC polymorphism generation when intron sequences are studied. The data obtained confirm that the B*83:01 allele is generated by gene conversion event including exon 2 and partial intron 1 and 2 between B*44 and B*56 alleles.