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Discovery of HLA‐B*480102 in Taiwanese
Author(s) -
Chen M. J.,
Chu C. C.,
Shyr M. H.,
Lin P. Y.,
Yang K. L.
Publication year - 2008
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.2007.00731.x
Subject(s) - human leukocyte antigen , allele , antigen , hla b , ethnic group , biology , genetics , gene , anthropology , sociology
Summary Human leucocyte antigen (HLA)‐B48, an antigen within 7C CREG (cross‐reacting group) (Steiner et al ., 2001) that cross‐reacts frequently with HLA‐B40 (i.e. HLA‐B60 and ‐B61) group of antibodies serologically, can be found in Alaskan Natives (Leffell et al ., 2002), Amerindians (Martinez‐Naves et al ., 1997), African Americans, Caucasians, and Oriental ethnicities (Mori et al ., 1997; Schipper et al ., 1997; Cao et al ., 2001; Middleton et al ., 2004; Hong et al ., 2005; Itoh et al ., 2005; Lee et al ., 2005; Ogata et al ., 2007). Sequencing investigations demonstrated that the common allele encoding the B48 antigen is B*4801 (Belich et al ., 1992). To date, there are at least 16 WHO recognized B*48 alleles according to the most recent report from the WHO nomenclature committee (Marsh et al ., 2005). Here we report a newly discovered allele B*480102, a variant of B*4801, detected in a 55‐year‐old Taiwanese patient of Minan origin (southern China).