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Characterization of a novel HLA‐DRB1*04 allele (DRB1*0460) in the Italian population
Author(s) -
Frison S.,
Rinaldini C.,
Pagoda M.,
Brambilla C.,
Poli F.
Publication year - 2007
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.2006.00641.x
Subject(s) - genetics , hla drb1 , allele , human leukocyte antigen , exon , biology , gene , antigen
Summary We report the identification of a novel HLA‐DRB1*04, officially named DRB1*0460. It was detected during performing HLA‐DRB1 high resolution typing by DNA sequencing‐based method. The exon 2 nucleotide sequence of DRB1*0460 is identical to that of DRB1*040301 except at codon 63 (AGC→AAC), changing the encoded serine to asparagine.
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