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A novel HLA‐B*2730 allele found in a Slovene patient affected with IgA nephropathy
Author(s) -
VidanJeras B.,
Kunilo S.,
Fae I.,
Kandus A.,
Fischer G. F.
Publication year - 2006
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.2006.00629.x
Subject(s) - allele , human leukocyte antigen , nephropathy , immunology , medicine , genetics , biology , antigen , endocrinology , gene , diabetes mellitus
Summary A novel allele HLA‐B*2730 and the haplotype HLA‐A*03‐B*2730‐Cw*02‐DRB1*16‐DRB5 have been found in a Slovene patient and his mother. The exon 2 sequence is identical to that of HLA‐B*2702, and the exon 3 sequence is identical to that of HLA‐B*2719. A possible mechanism for the generation of B*2730 is a gene conversion event.
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