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HLA‐DPB 1 POLYMORPHISM IN SEVEN SOUTH AMERICAN INDIAN TRIBES IN COLOMBIA
Author(s) -
Briceno I.,
Gomez A.,
Bernal J. E.,
Papiha S. S.
Publication year - 1996
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1996.tb00118.x
Subject(s) - tribe , allele , human leukocyte antigen , polymorphism (computer science) , biology , genetic diversity , allele frequency , genetics , diversity (politics) , geography , ethnology , demography , anthropology , gene , history , sociology , population , antigen
SUMMARY HLA‐DPB 1 allele frequencies were investigated in seven geographically and linguistically distinct Amerindian tribes of Colombia. Allele *1301 was found only in the Embera tribe living along the Pacific coast, while allele *0101 was found only in two individuals of the Wayuu tribe inhabiting the Guajira desert. Significant geographical variation was observed in the other two alleles (*1401 and *0402), which were found in all seven tribal groups. The possible reasons for this restricted polymorphism and the genetic diversity found in the investigation are discussed.