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CORRELATION OF IgA2 SERUM LEVELS IN PARENT‐OFFSPRING PAIRS
Author(s) -
Benedictis G. De,
Rose G.,
Brancati C.
Publication year - 1988
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1988.tb00431.x
Subject(s) - offspring , correlation , positive correlation , demography , biology , genetics , developmental psychology , psychology , medicine , pregnancy , mathematics , sociology , geometry
SUMMARY IgA2 serum levels were measured by ELISA in 120 healthy subjects from 40 nuclear families (both parents and one offspring). No sex‐associated difference was observed. Moreover, the IgA2 serum levels proved to be significantly correlated in parent‐offspring pairs ( r =0·55; P < 0·001), while there was no significant correlation in mother‐father pairs of the same family. The data suggest that the serum level of the IgA2 subclass is genetically controlled.