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Ir GENE FOR BOVINE INSULIN IN THE RAT MAPS TO RT1.B β
Author(s) -
Mizuno K.,
Inomata T.,
Tsuchimoto S.,
Matsuno Y.,
Niiyama T.,
Fujii H.,
And T. Natori,
Aizawa M.
Publication year - 1987
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1987.tb00376.x
Subject(s) - insulin , gene , human insulin , chemistry , biology , microbiology and biotechnology , computational biology , genetics , endocrinology
SUMMARY The genetic control of the immune response to bovine insulin (BI) in the rat was investigated. As a result of experiments utilizing two intra‐MHC recombinant rats and of blocking experiments with monoclonal antibodies against MHC class II antigens, an immune response gene for BI in the rat could be mapped to the RT1.B β locus.