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ABERRANT H‐2‐LIKE ALLOSPECIFICITIES ON K36.16 THYMOMA
Author(s) -
Festenstein H.,
Hut K. M.
Publication year - 1986
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1986.tb01091.x
Subject(s) - monoclonal antibody , immunoprecipitation , thymoma , antibody , microbiology and biotechnology , monoclonal , biology , gene , chemistry , immunology , genetics
SUMMARY The K36.16 thymoma expresses an H‐2D d ‐like allospecilicity as detected by the 34‐5‐8 monoclonal antibody directed against H‐2D d using immunoprecipitation techniques. This monoclonal antibody gives a negative result by radio‐immune assay but other anti‐D d antibodies react positively with this tumour. These results confirm and extend previous observations and are attributed to probable gene‐conversion events possibly involving a donor gene from the QafTla region, the products of which cross‐react with D d .