Premium
IMMUNOGLOBULIN ALLOTYPES IN A CHINESE POPULATION: COMPARISON OF HAPLOTYPE FREQUENCIES WITH OTHER ASIAN GROUPS
Author(s) -
Lange Gerda de,
FaMing Zhong,
Henke Jürgen,
Feng Zongchen,
Bernhardt Ralph,
Leeuwen Fred,
Eede Peter
Publication year - 1985
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1985.tb00846.x
Subject(s) - haplotype , biology , china , chinese population , allele frequency , population , genetics , gene , demography , allele , geography , genotype , sociology , archaeology
SUMMARY Two groups of Chinese individuals of the city of Wuhan in the People's Republic of China, consisting of 98 blood bank donors and 278 workers in a steel factory, respectively, have been typed for G1m, G2m, G3m, A2m and Km allotypes. The Gm‐A2m haplotype frequencies as well as the Km gene frequencies appeared to be quite similar in these two groups of people, the main haplotypes being Gm af;n;b A2m 2 and Gm za…;g A2m 1 . After joining the data of the two groups, the frequencies of the main Gm haplotypes and the A2m and Km gene frequencies have been compared with those of six other Asian populations. In Asia, going from the south to the north, an increasing frequency of Gm za;…;g and a decreasing frequency of Gm af;n;b were observed. The frequencies found in the investigated Chinese population lie between the frequencies found in the Chinese from Taiwan and the Japanese.