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C4* A6BQO: A NEW C4 HAPLOTYPE
Author(s) -
Skanes Verna,
Larsen Bodil
Publication year - 1984
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1984.tb00823.x
Subject(s) - haplotype , major histocompatibility complex , genetics , biology , allele , gene
SUMMARY A C4 haplotype containing C4 * A6 without C4 * B1 is described. It occurred in the MHC haplotype HLA‐AL, Cw5, Bw44, C2*1, BF*S, C4*A6BQO, DR3, GLO 2. This haplotype was observed in five of eight siblings, including the propositus who was in renal failure. The C4A6 was not haemolytically active and this new haplotype is therefore of particular interest since it is functionally equivalent to the rare C4‐deficient haplotype C4*AQOBQO .