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MURINE IN VIVO CARRIER ‐SPECIFIC IgG MEMORY TO DNP‐FICOLL: VARIATION AMONG INBRED STRAINS
Author(s) -
Schott C. F.,
Merchant B.
Publication year - 1982
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1982.tb00983.x
Subject(s) - ficoll , biology , immunological memory , inbred strain , immunology , in vivo , phenotype , antigen , hemocyanin , microbiology and biotechnology , genetics , in vitro , immunity , gene , immune system , peripheral blood mononuclear cell
SUMMARY BALB/cAnN and C3H/HeN mice were primed and challenged with DNP‐Ficoll, a thymic independent (TI‐2) antigen. They developed significant carrier‐specific IgG memory responses: DNP‐pneumococcal polysaccharide or DNP‐hemocyanin challange did not elicit memory responses. NZB/B1NJ mice failed to develop this memory response. Genetically controlled events apparently regulate the phenotypic expression of this effect.