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ATYPICAL TRANSMISSION OF ABO BLOOD GROUPS IN A FRENCH FAMILY
Author(s) -
Badet J.,
Lopez M.,
Habibi B.,
Cartron J. P.,
Noel A.,
Salmon D.,
Seger J.,
Salmon C.
Publication year - 1982
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1982.tb00788.x
Subject(s) - abo blood group system , saliva , group a , blood group antigens , blood type (non human) , biology , genetics , immunology , antigen , medicine , biochemistry
Summary A group AB mother (Mrs P.D.) gave birth to a group O female baby (C.D.). Extensive study of the blood group genetic markers in both the parents and the child, carried out on several occasions, showed nothing unusual outside the ABO system. Mrs P.D. then, gave birth to a second female baby who was also group O. Mrs P.D. had normal amounts of A, B, H and Lewis antigens in her saliva. The H, A and B agglutinability of her red cells was in the range of normal A 2 B group. This A 2 B blood group was characterized by very low A gene‐specified glycosyltransferase activity in serum. Moreover this activity was undettable in red blood cell membranes. These results are discussed in the light of various hypotheses in order to explain this unusual transmission of ABO blood group.