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PROPERDIN FACTOR B POLYMORPHISM IN BLACK AMERICANS
Author(s) -
Budowle B.,
Go R. C. P.,
Barger B. O.,
Acton R. T.
Publication year - 1981
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1981.tb00960.x
Subject(s) - properdin , polymorphism (computer science) , biology , allele frequency , agarose gel electrophoresis , genetics , demography , agarose , negroid , antibody , gene , allele , microbiology and biotechnology , population , complement system , sociology
SUMMARY Properdin factor B is a genetically‐controlled polymorphism that can be demonstrated by agarose gel electrophoresis. The Bf gene frequencies were determined for 194 blacks from the south‐eastern United States. The frequencies for Bf‐F, Bf‐S, Bf‐F1 , and Bf‐Sl are 0.626, 0.327, 0.034, and 0.013, respectively. The south‐eastern blacks have similar Bf frequencies to the South African blacks; however, both these groups are different from blacks from Boston. The frequency differences between south‐eastern blacks and Boston blacks may be due to racial admixture differences found in the two populations.