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A MARMOSET T LYMPHOMA WHICH FUNCTIONS AS A HUMAN AMPLIFIER T CELL
Author(s) -
Marchalonis J. J.,
Strelkauskas A. J.
Publication year - 1981
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1981.tb00956.x
Subject(s) - marmoset , biology , antibody , antigen , virology , secretion , t cell , lymphoma , phylogenetic tree , in vitro , microbiology and biotechnology , immunology , genetics , gene , immune system , ecology , biochemistry
SUMMARY A long‐term in vitro grown T cell line derived from a cotton‐topped marmoset (Saguinus oedipus) ) infected with Herpesvirus saimiri was found to share surface antigens with human amplifier T cells and to augment the capacity of human B cells to secrete immunoglobulin. This is the first demonstration of T/B collaboration across such a large phylogenetic barrier and might have interesting implications for understanding the nature of molecular interactions mediating cell/cell cooperation.