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XENOANTISERA TO DR w ALLOSPECIFICITIES
Author(s) -
Belvedere M.,
Pellegrino M. A.,
Ferrone S.
Publication year - 1980
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1980.tb00718.x
Subject(s) - cytotoxic t cell , antigen , complement (music) , antibody , immunology , human leukocyte antigen , complement dependent cytotoxicity , biology , microbiology and biotechnology , chemistry , genetics , in vitro , monoclonal antibody , gene , phenotype , antibody dependent cell mediated cytotoxicity , complementation
Summary The specificity of DR xenoantisera was assessed by testing them with a panel of HLA typed B‐lymphocytes in a cytotoxic test with rabbit or human complement. The pattern of reactions of some xenoantisera correlated with DR allospecificities. These results confirm that injection of DR antigens across species barrier can elicit antibodies to DR allospecificities.