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TWO APPARENTLY HEALTHY JAPANESE INDIVIDUALS OF TYPE M k M k HAVE ERYTHROCYTES WHICH LACK BOTH THE BLOOD GROUP MN AND Ss‐ACTIVE SIALOGLYCOPROTEINS
Author(s) -
Tokunaga E.,
Sasakawa S.,
Tamaka K.,
Kawamata H.,
Giles C. M.,
Ikin E. W.,
Poole J.,
Anstee D. J.,
Mawby W.,
Tanner M. J. A.
Publication year - 1979
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1979.tb00693.x
Subject(s) - sialoglycoproteins , glycoprotein , antibody , antigen , microbiology and biotechnology , blood group antigens , blood donor , biology , immunology , chemistry
Summary A Japanese blood donor (H. T.) and his brother (M. S.) are the first homozygous M k M k individuals described; their red cells lack, as expected, known antigens of the MNSs blood group system and also have no demonstrable MN‐active and Ss‐active glycoproteins. Both M k M k individuals have a naturally occurring atypical antibody in their serum. The antibody in the serum of H. T. is inhibited by MNSs‐active glycoprotein preparations from normal erythrocytes.