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IMMUNOGLOBULIN ALLOTYPES AND RESPONSE TO TETANUS TOXOID IN PAPUA, NEW GUINEA
Author(s) -
Schanfield M. S.,
Wells J. V.,
Fudenberg H. H.
Publication year - 1979
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1979.tb00686.x
Subject(s) - toxoid , tetanus , biology , new guinea , antibody , haplotype , immunology , antibody response , virology , genetics , vaccination , genotype , gene , ethnology , history
Summary The data indicates that Papuans with the Austronesian haplotype Gm f,a;b produce significantly higher levels of tetanus specific antibody, than Papuans without this haplotype, suggesting that response to tetanus toxoid in man is associated with the Gm phenotype of the individual. Km (1) status was not related to response.