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COMPARISON OF HAPLOTYPES OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN THE RAT I. THE Ag‐B7 (H‐1 8 ) AND Ag‐B8 (H‐1 k ) HAPLOTYPES
Author(s) -
Scaron;tark O.,
Günther E.,
Kunz H. W.,
Gill T. J.
Publication year - 1977
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1977.tb00924.x
Subject(s) - haplotype , congenic , histocompatibility , major histocompatibility complex , biology , genetics , chemistry , antigen , gene , genotype , human leukocyte antigen
SUMMARY Two haplotypes of the major histocompatibility complex of the rat, Ag‐B7 and Ag‐B8, have been compared with known H‐1 haplotypes using the F 1 skin‐graft test and the dextran haemagglutination test. Both of these Ag‐B haplotypes were different from the known H‐1 haplotypes and determined different private specificities. The Ag‐B7 haplotype was denoted as H‐1 g and the Ag‐B8 haplotype as H‐1 k . The complex structure of the serologically detected antigenic products of these haplotypes was determined by means of H‐1 congenic lines.