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HL‐A8 AND THE IMMUNE RESPONSE TO VARIOUS ANTIGENS
Author(s) -
Scott B. B.,
Cooke E. Mary,
Hambling M. H.,
Rajah S. M.,
Swinburne M. L.,
Losowsky M. S.
Publication year - 1976
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1976.tb00571.x
Subject(s) - immune system , immunology , antigen , gluten , antibody , histocompatibility , major histocompatibility complex , biology , virology , human leukocyte antigen , biochemistry
SUMMARY The possession of the histocompatibility antigen HL‐A8 has been correlated with serum levels of antibodies to gluten and a variety of other dietary, viral, and bacterial antigens and autoantigens. The only significant correlation with HL‐A8 was of raised levels of gluten antibody. Thus it seems that HL‐A8 may be associated with an enhanced immune response specifically to gluten, and not with a generally enhanced immunological responsiveness as has been suggested.