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LINKAGE RELATIONSHIPS OF THE LOCI OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN FAMILIES WITH A RECOMBINATION IN THE HLA REGION
Author(s) -
Bijnen A. B.,
Schreuder Ieke,
Khan P. Meera,
Allen F. H.,
Giles C. M.,
Los W. R. T.,
Volkers W. S.,
Rood J. J.
Publication year - 1976
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1976.tb00570.x
Subject(s) - genetics , human leukocyte antigen , biology , recombination , linkage (software) , genetic linkage , major histocompatibility complex , chromosome , gene , histocompatibility , complete linkage , haplotype , allele , antigen , genotype , single nucleotide polymorphism
SUMMARY A number of families with an established recombination in the major histo‐compatibility complex has been investigated for markers known to be coded by genes of this linkage group. The results provide further data on the relative position of the loci for HLA‐A, HLA‐B, HLA‐C, HLA‐D, Bf, Chido, Rodgers and PGM 3 on chromosome 6. A positive lodscore for linkage between HLA and blood group P was found; lodscores between HLA and nineteen other markers were negative.