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A STUDY ON THE DETERMINANT STRUCTURE OF HUMAN SERUM ALBUMIN
Author(s) -
Bauer Klausdieter
Publication year - 1974
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1974.tb00319.x
Subject(s) - human serum albumin , human albumin , biology , continuation , albumin , antigen , serum albumin , evolutionary biology , computational biology , genetics , biochemistry , computer science , programming language
SUMMARY In continuation of earlier experimentation from this laboratory the antigenic structure of human serum albumin was determined by comparative determinant analysis (CDA). The results are a correction of an earlier report on the same subject; the importance of the standard control procedures of CDA is stressed. The results indicate the presence of at least six different antigenic determinants on the human molecule, two of which are shared only by primates, while the four others are common with other mammalian albumins as well. There is no human species‐specific determinant demonstrable. The structures of human and chimpanzee albumins were found to be identical.