Premium
ISOLATION OF AN ISOANTIGEN ASSOCIATED WITH LEUKOSIS‐SARCOMA VIRUS SUSCEPTIBILITY IN CHICKENS AND ITS RELATION TO HUMAN BLOOD‐GROUP MN SUBSTANCES
Author(s) -
Springer G. F.,
Desai Parimal R.,
Banatwala I.,
Tegtmeyer Herta,
Briles W. E.
Publication year - 1974
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1974.tb00307.x
Subject(s) - biology , antigen , virology , virus , sialic acid , proteases , retrovirus , human blood , immunology , microbiology and biotechnology , enzyme , biochemistry , physiology
SUMMARY The R 1 antigen of chicken red cells, which is associated with susceptibility to a subgroup B leukosis‐sarcoma virus, has been isolated. This antigen is cross‐related to structures on the human blood‐group MN antigens and, as in the latter, sialic acid is apparently part of its immunodominant grouping. R 1 antigen inhibited influenza viruses and to a lesser extent Vicia graminea anti‐N reagent. Plant proteases inactivated the antigen.