Premium
PLACENTAL AND FOETAL WEIGHTS ASSOCIATED WITH ALLOANTIGENIC DIFFERENCES AND MULTIPARITY IN MICE
Author(s) -
Breyere Edward J.,
Zarick Pamela P.,
Griffin Bill R.
Publication year - 1974
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1974.tb00306.x
Subject(s) - placenta , fetus , biology , andrology , isoantigens , embryo , antigen , pregnancy , immunology , medicine , genetics
SUMMARY The effects of varying degrees of multiparity on placental and foetal weights were examined in BALB/c female mice pregnant by either BALB/c or C3H males. Continual decreases in placental weights are observed through third pregnancies followed by progressive increases in both syngeneic and allogeneic placentas. In syngeneic pregnancies, foetal weights are generally proportional to placental weights, but those of allogeneic pregnancies tend to oppose placental weights. Evidence is presented that placental weights are also influenced by foetus‐specific antigens and the genotype of previous litters. In this strain combination, placental weights reflect changes in maternal reactivity different from those previously reported with tumour allografts.