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α 2 ‐MACROGLOBULIN POLYMORPHISM: A NEW GENETIC SYSTEM DETECTED BY IMMUNOELECTROPHORESIS
Author(s) -
Gallango Maria L.,
Castillo Omar
Publication year - 1974
Publication title -
international journal of immunogenetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 47
eISSN - 1744-313X
pISSN - 1744-3121
DOI - 10.1111/j.1744-313x.1974.tb00304.x
Subject(s) - macroglobulin , mendelian inheritance , genetics , polymorphism (computer science) , biology , immunoelectrophoresis , allele , microbiology and biotechnology , gene , antibody
SUMMARY A rabbit anti‐human serum allowed the identification of a new human polymorphism of the α 2 ‐macroglobulin. This polymorphism is represented by three variants: A, having a fast electrophoretic mobility; B, intermediate mobility; and C having a slower migration and the three combinations: AB, AC and BC. Preliminary genetic studies suggest that inheritance is of Mendelian autosomal co‐dominant type.