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Neurocutaneous melanosis and negative fluorodeoxyglucose positron emission tomography
Author(s) -
Li LaiFung,
Leung ShueCheong,
Chan SiuKi,
Leung Gilberto KaKit
Publication year - 2010
Publication title -
surgical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.109
H-Index - 10
eISSN - 1744-1633
pISSN - 1744-1625
DOI - 10.1111/j.1744-1633.2010.00498.x
Subject(s) - leptomeninges , medicine , melanosis , positron emission tomography , fluorodeoxyglucose , melanoma , magnetic resonance imaging , pathology , central nervous system , radiology , cancer research
Neurocutaneous melanosis is a rare condition characterized by cutaneous melanocytic naevi and the presence of melanocytes in the leptomeninges. It is commonly associated with malignant melanoma formation in the central nervous system (CNS) with poor prognosis. Herein, we report a 13‐year‐old boy with neurocutaneous melanosis who presented with seizure with diffuse CNS malignant melanoma, as demonstrated by magnetic resonance imaging (MRI). 18F‐fluorodeoxyglucose positron emission tomography (PET) was carried out, but was unable to detect the CNS involvement. So far, this is the first report involving the use of PET in neurocutaneous melanosis and we suggest that MRI is more sensitive than PET with 18F‐fluorodeoxyglucose in such conditions.