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Sphincter‐preserving excision of rectal gastrointestinal stromal tumour following neoadjuvant therapy
Author(s) -
Wong Dennis ChungTak,
Chung Cliff ChiChiu,
Yau Kelvin KwokKay,
Wong James CheukHoo,
Li Michael KaWah
Publication year - 2008
Publication title -
surgical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.109
H-Index - 10
eISSN - 1744-1633
pISSN - 1744-1625
DOI - 10.1111/j.1744-1633.2007.00383.x
Subject(s) - medicine , imatinib mesylate , stromal cell , neoadjuvant therapy , imatinib , oncology , sphincter , surgery , cancer , breast cancer , myeloid leukemia
Imatinib mesylate is the treatment of choice for metastatic and unresectable gastrointestinal stromal tumour. With evidence showing overall excellent response rates, its potential role in the neoadjuvant setting is currently being explored. In addition to improving resectability of advanced tumours, the downstaging effect may also have potential functional advantages. We herein report a successful case of sphincter‐preserving resection of a low rectal gastrointestinal stromal tumour following neoadjuvant therapy with imatinib.